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Items starting with A

Alkaline Phosphatase (ALP) Isoenzymes (APISO)

Reported as a comment:

ALP1	Predominantly liver isoenzyme present.
ALP2	Predominantly bone isoenzyme present.
ALP3	Both liver and bone isoenzymes are present in approximately equal concentrations.
ALP4	Biliary isoenzyme also present.
ALP5	Intestinal isoenzyme also present: this may indicate intestinal disease but also may occur in the absence of pathology in some individuals of blood group O and B after eating.
ALP	Alkaline phosphatase isoenzyme analysis is not indicated when the total alkaline phosphatase is not markedly raised.

Referred Work Biochemistry

Alpha Amino Adipic Semialdehyde (AASA, ASA)

Provided by referral laboratory.

Referred Work

https://www.ucl.ac.uk/ich/services/lab-services/mass_spectrometry/services_and_costs

Alpha Amino Adipic Semialdehyde (AASA, ASA)

Provided by referral laboratory.

Referred Work

https://www.ucl.ac.uk/ich/services/lab-services/mass_spectrometry/services_and_costs

Alpha Fetoprotein (AFP)

0.7-7.3 kU/L(when used as a tumour marker)

(Source: Abbott Diagnostics)

Biochemistry

https://pinboard.in/u:duty_biochemist/t:AFP/

Alpha Subunits (ASU)

Adult males and pre-menopausal females: <1.0 IU/L
Post-menopausal or mid-cycle females: <3.0 IU/L

Pregnancy - there is a 0.1% cross reaction with hCG resulting in very high ASU results in pregnancy.

Results should be interpreted along with the serum LH, FSH and TSH results and renal function tests.

Referred Work Biochemistry

Alpha-1-Antitrypsin (A1AT or AAT)

Adult range 1.1 - 2.1 g/L.

Age related ranges are available by contacting the Immunology department.

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/alpha1-antitrypsin/tab/glance

alpha-1-antitrypsin (A1AT or AAT) PCR genotype

Referred Work Immunology

https://pinboard.in/u:duty_biochemist/t:Alpha-1-Antitrypsin/

Alpha-1-Antitrypsin (A1AT or AAT) Phenotyping

M pattern

Immunology

http://www.sas-centre.org/assays/protein-reference-units/a1-antitrypsin-phenotyping

Alpha/beta Carotenes

Alpha carotene <0.25 umol/L

Beta carotene 0.19-0.89 umol/L

Referred Work Biochemistry

Aluminium

<0.37 umol/L: Normal (no history of CRF).

<2.22 umol/L: Desirable in CRF patients.

>2.22 umol/L: Excessive accumulation.

>3.70 umol/L: Cause for concern, high risk of toxicity in children.

>7.41 umol/L: Urgent action required; High Risk of toxicity in all.

Toxicology

Toxic range: > 0.2 mg/L. Amfetamine concentrations above 0.50 mg/L have been linked to fatalities, but in regular amfetamine users, blood concentrations may range up to 3 mg/L without toxic effects. (Schulz et al. Critical Care 2012, 16:R136).

Toxicology

Amikacin Antibiotic Assay

For once daily dosing aim for pre-dose levels (taken 15 minutes before dose) of <5mg/L and post dose levels (taken 1 hour post dose) of >35mg/L.

For multiple daily dosing aim for pre-dose levels of <10mg/L and post dose levels of 20-30mg/L.

Biochemistry

Amino Acids

Provided by Reference laboratory

Referred Work Biochemistry

Amiodarone

Test not available. To discuss further contact duty biochemist (2506)

Referred Work Biochemistry

Amitriptyline & Nortriptyline

In therapeutic use, plasma concentrations for the two drugs combined do not usually exceed 300 ug/L, with symptoms associated with toxicity observed at levels greater than 500 ug/L. (Clarke's Analysis of Drugs & Poisons, Third Edition)