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Immunology

Phospholipase A2 receptor antibody (PLA2r)

Phospholipase A2 receptor antibody (PLA2r)

<14 = Negative
14-20 = Borderline
>20 = Positive

results between 3 and 19.9 will be tested via IFA test at UoB

Proteinase 3  PR3 antibody

Proteinase 3 PR3 antibody

Negative = <2.0 U/mL

Weak positive =2.0 - 3.0 U/mL

Positive = >3.0 u/mL

A normal result would be negative

reference range as quoted by Manufacturer PHADIA http://www.phadia.com/Global/A%20Document%20Library/Autoimmunity/Promotion%20Material/Product%20-%20Peformance%20-%20Detailer%20Info/Performance_Folder_%20EliA%20PR3S%20MPOS.pdf

Dedicated QuantiFERON-Gold IT samples (NIL, TB, MITO) available in all Trust Phlebotomy Departments, and available by request to Immunology Dept ext 42184).

Quantiferon Plus Interferon gamma release assay for TB

A negative result suggests no active immune response to Mycobacterium Tuberculosis. A positive results indicates a response to MTB infection, but does not distinguish between active and latent disease. The test cannot be used to exclude active infection, since false-negative results do occur. It should always be interpreted in the context of other clinial and laboratory features.

Due to biological variations, re-testing borderline results is recommended. Indeterminate results indicate failure of positive or negative controls which may be due to technical or patient-specific factors.  Re-testing recommended.  

CMV IGRA assay specific tubes Please contact Immunology for details

QuantiFERON-CMV (QF-CMV) In-tube interferon gamma release (IGRA) test for evaluating anti - CMV immunity.

Results reported as interpretive comments: Anti CMV immunity NOT detected Anti-CMV immunity detected Result indeterminate for CMV responsiveness

CMV IGRA assay specific tubes Please contact Immunology for details

QuantiFERON-CMV (QF-CMV) In-tube interferon gamma release (IGRA) test for evaluating anti - CMV immunity.

Results reported as interpretive comments: Anti CMV immunity NOT detected Anti-CMV immunity detected Result indeterminate for CMV responsiveness

Rheumatoid Factor (RF)

Rheumatoid Factor (RF)

Up to 30 IU/mL = Negative

30-50= Weak Positive

Greater than 50 IU/mL = Positive

Serum Free Light Chains

Serum Free Light Chains

Reference Ranges updated 10/10/2024

Age <70 yrs

Serum free kappa light chain 6.3- 39.0 mg/L

Serum free lambda light chain 5.9- 36.7 mg/L

Free kappa: Free lambda ratio = 0.44 - 2.16

Age >=70 yrs

Serum free kappa light chain 7.0- 55.8 mg/L

Serum free lambda light chain 6.4- 48.0 mg/L

Free kappa: Free lambda ratio = 0.46 - 2.59

Specific Antibodies: Haemophilus influenza Group B

Specific Antibodies: Haemophilus influenza Group B

Minimum protective level 0.15 ug/mL

Optimum protective level >1.0 ug/mL

 

Specific Antibodies: Pneumococcus

Specific Antibodies: Pneumococcus

DEPENDS ON THE AGE AND IMMUNISATION STATUS

Specific Antibodies: Tetanus

Specific Antibodies: Tetanus

Minimum protective level 0.01 iu/mL

Optimum protective level>0.1 iu/mL

Long term protection >1.0 iu/mL

WHO publication Immunological basis for immunisation series Module 3 Tetanus update 2006

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