Department

Biochemistry

CTX1

Preferred Sample Type

CTX bone marker (Collagen Type I cross-linked C telopeptide; bone markers)

Suitable Specimen Types

EDTA Plasma

0.5 mL minimum plasma

Specimen Transport

Frozen.

Sample Processing in Laboratory

Separate and freeze plasma within 24 hours of specimen collection.

Sample Preparation

Spin and freeze plasma

Turnaround Time

7 days

Sample Stability

CTX is relatively stable in EDTA containers - plasma should be separated and frozen within 24 hours of specimen collection.

CTX bone marker (Collagen Type I cross-linked C telopeptide; bone markers)

Patient Preparation

Suggest take samples for monitoring at approximately the same time of day to aid interpretation of results. Results may be affected by diurnal variation (highest before waking, lowest mid afternoon) and non-fasted stated (~20% decreased post-prandial).

Reference Range

Adults
Male >21 y		Pre-menopausal females		Post-menopausal females
0.154 to 0.771 ug/L		0.121 to 0.747 ug/L		0.189 to 1.003 ug/L
Paediatrics - females
<6 y	7 to 11 y		12 to 16 y		17 to 21 y
0.179 to 1.690 ug/L	0.300 to 1.978 ug/L		0.151 to 1.912 ug/L		0.109 to 1.130 ug/L
Paediatrics - males
<6 y	7 to 11 y		12 to 16 y		17 to 21 y
0.446 to 1.756 ug/L	0.659 to 1.975 ug/L		0.393 to 2.131 ug/L		0.263 to 1.554 ug/L

From 19/01/2026, samples for CTX will be analysed at QEHB.

Source of Reference Range

IDS kit insert

Specifications

EQA Scheme?: Yes