Department

Local code : CH50B

Preferred Sample Type

Suitable Specimen Types

Serum

5-10 mL

Specimen Transport

Transport to laboratory ideally within one hour post venepuncture If from external source arrange for sample to be Spun separated and frozen at interim site prior to sending to Immunology at BHH.

Sample Processing in Laboratory

Ideally separate and freeze at – 80 C within one hour of venepuncture, Samples can be accepted up to 48 hours post venepuncture.

Sample Preparation

Arrange for sample to be separated at an interim site and subsequentlytransport frozen to lab

Turnaround Time

up to 4 weeks

Sample Stability

To be stored at -70^oC or below.

CH50

General Information

Some indications: Hereditary complement deficiencies recurrent meningitis, familial SLE

Patient Preparation

None

Notes

CH50 results should always be interpreted in conjunction with Complement levels.

Reference Range

Normal range 42 -95U/mL,

Low 30 -42 U/mL,

Absent <30 U/mL.

Source of Reference Range

Provided by The Binding Site Limited

Specifications

EQA Scheme?: No
EQA Status:
No scheme available