PLA2RS
Preferred Sample Type
Suitable Specimen Types
- Serum
4 mL
Turnaround Time
14 daysSample Stability
Stored at 4CPhospholipase A2 receptor antibody (PLA2r)
General Information
Phospholipase A2 receptor is the target autoantigen in idiopathic membranous nephropathy (IMN). Antibodies to PLA2r are found in up to 75% of patients with IMN naive to immunosuppression and can be used as a diagnostic marker for IMN. PLA2r antibodies are found to be high in active disease and low/normal in complete remission and can be used to monitor disease activity.
Patient Preparation
No special requirements
Reference Range
<14 = Negative
14-20 = Borderline
>20 = Positive
results between 3 and 19.9 will be tested via IFA test at UoB
Specifications
- EQA Scheme?: Yes
- EQA Status: Pilot scheme run through UK NEQAS Sheffield PRU