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Items tagged with ANTIBIOTIC ASSAY

Amikacin Antibiotic Assay

For once daily dosing aim for pre-dose levels (taken 15 minutes before dose) of <5mg/L and post dose levels (taken 1 hour post dose) of >35mg/L.

For multiple daily dosing aim for pre-dose levels of <10mg/L and post dose levels of 20-30mg/L.

Multiple Daily Dosing

Pre dose (trough) blood sample 15 mins before dose <2mg/L

Post dose (peak) blood sample 1 hour after dose 5 - 10mg/L

In endocarditis pre dose <1mg/L and post dose 3 - 5mg/L

N.B. Ranges and comments DO NOT apply to Renal patients

Once Daily Dosing

Post-dose only taken between 6 and 14 hours after dose. Times of dosing and sampling must MUST be given on request form.

Refer to Urban & Craig nomogram to interpet

Please refer to Antibiotic guidelines on the HEFT website for further information (http://pharmacy/?page_id=922)

Pre dose (trough) level 10- 15 mg/L.

For more information please see pharmacy guidance (http://pharmacy/?page_id=922)