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Items starting with I

IGF-1 (Insulin-like Growth Factor)

IGF-1 (Insulin-like Growth Factor)

Reference range provided by referral laboratory. Please note new reference range 27/09/2016 (analysed by IDS iSYS assay)

Age

Female

Male

LLN (nmol/L)

ULN (nmol/L)

LLN (nmol/L)

ULN (nmol/L)

0

2.3

19.1

1.9

19.7

1

2.6

20.9

2.4

23.4

2

3.0

23.1

2.8

26.7

3

3.5

26.0

3.3

29.3

4

4.2

29.2

3.7

31.6

5

4.8

32.3

4.1

33.9

6

5.4

35.3

4.7

36.8

7

6.2

39.1

5.4

40.7

8

7.4

44.5

6.4

46.0

9

8.9

51.9

7.6

52.5

10

10.9

60.9

9.1

60.0

11

13.0

70.4

10.7

67.6

12

15.0

78.4

12.2

74.2

13

16.5

83.4

13.5

79.0

14

17.4

84.8

14.5

81.3

15

17.5

82.7

15.0

80.9

16

17.0

77.9

15.1

78.4

17

16.1

71.5

14.8

74.2

18

14.9

64.5

14.3

69.0

19

13.7

57.8

13.6

63.4

20

12.7

52.1

12.8

58.0

21-25

11.0

42.3

10.9

45.1

26-30

10.1

35.5

9.8

36.0

31-35

9.5

32.0

9.3

31.6

36-40

8.9

29.5

9.1

29.6

41-45

8.1

26.9

8.3

27.5

46-50

7.4

25.4

7.7

26.4

51-55

6.9

25.0

7.3

26.3

56-60

5.9

22.7

6.6

25.4

61-65

5.4

22.0

6.2

25.0

66-70

5.1

22.0

6.0

25.5

71-75

4.7

21.7

5.4

24.5

76-80

4.6

22.1

5.1

24.0

81-85

4.6

23.4

4.8

23.8

86-90

4.3

23.4

4.6

23.8

IGFBP-3 (Insulin-Like Growth Factor Binding Protein-3)

IGFBP-3 (Insulin-Like Growth Factor Binding Protein-3)

Age-related reference ranges provided by reference laboratory.

IgG4

IgG4

Age related reference ranges ( all values in g/L):-

Cord Blood  IgG1=3.6-8.4, IgG2=1.2-4.0, IgG3 = 0.3-1.5, IgG4 = <0.5

6 months IgG1=1.5-3.0, IgG2= 0.3-0.5, IgG3 = 0.1-0.6, IgG4= <0.5

2 years  IgG1= 2.3-5.8, IgG2= 0.3-3.9, IgG3= 0.1-0.8, IgG4 = <0.5

5 years  IgG1= 2.3-6.4, IgG2= 0.7-4.5, IgG3= 0.1-1.1, IgG4 = <0.8

10 years IgG1= 3.6-7.3, IgG2= 1.4-4.5, IgG3= 0.3-1.1, IgG4 = <1.0

15 years IgG1= 3.8-7.7, IgG2= 1.3-4.6, IgG3= 0.2-1.2, IgG4 = <1.1

Adult     IgG1=3.2-10.2, IgG2= 1.2-6.6, IgG3= 0.2-1.9, IgG4 = <1.3

 

Imipramine and Desipramine

Imipramine and Desipramine

Therapeutic concentrations of imipramine range between 50 to 150 ug/L, with the total sum of imipramine and desipramine between 150 and 300 ug/L. 

Imipramine and Desipramine

Imipramine and Desipramine

Therapeutic concentrations of imipramine range between 50 to 150 ug/L, with the total sum of imipramine and desipramine between 150 and 300 ug/L. 

Immunoglobulin A (IgA)

Immunoglobulin A (IgA)

Age related reference ranges

Cord <0.02 g/L,       0-2 weeks 0.01-0.08 g/L

2-6 weeks 0.02-0.15g/L,  6-12 weeks 0.05-0.4 g/L

3-6 months 0.1-0.5g/L, 6-9 months 0.15-0.7g/L, 9-12 months 0.2-0.7g/L

1-2yrs 0.3-1.2 g/L, 2-3yrs 0.3-1.3 g/L, 3-6yrs 0.4-2.0g/l

6-9yrs 0.5-2.4 g/L, 9-12yrs 0.7-2.5 g/L, 12-15yrs 0.8-2.8 g/L

15-45yrs 0.8-2.8 g/L   >45yrs 0.8-4.0 g/L

   

Immunoglobulin G (IgG)

Immunoglobulin G (IgG)

Age related reference range:-

Cord 5.2-18.0g/L, 

0-2 weeks 5.0-17.0 g/L, 2-6 weeks 3.9-13.0 g/L, 6-12 weeks 2.1-7.7 g/L

3-6 months 2.4-8.8 g/L, 6-9 months 3.0-9.0 g/L,  9-12 months 3.0-10.9 g/L

1-2 yrs 3.1-13.8 g/L, 2-3 yrs 3.7-15.8 g/L, 3-6 yrs 4.9-16.1 g/L

6-9 yrs 5.4-16.1 g/L, 9-12 yrs 5.4-16.1 g/L 12-15 yrs 5.4-16.1 g/L

15-45 yrs 6.0-16.0 g/L   >45yrs 6.0-16.0 g/L  

Immunoglobulin M (IgM)

Immunoglobulin M (IgM)

Age related reference range:-

Cord 0.02-0.2g/L, 

0-2 weeks 0.05-0.2 g/L, 2-6 weeks 0.08-0.4 g/L, 6-12 weeks 0.15-0.7 g/L

3-6 months 0.2-1.0 g/L, 6-9 months 0.4-1.6 g/L,  9-12 months 0.6-2.1 g/L

1-2 yrs 0.5-2.2 g/L, 2-3 yrs 0.5-2.2 g/L, 3-6 yrs 0.5-2.0 g/L

6-9 yrs 0.5-1.8 g/L, 9-12 yrs 0.5-1.8 g/L 12-15 yrs 0.5-1.9 g/L

15-45 yrs 0.5-1.9 g/L   >45yrs 0.5-2.0 g/L  

Immunoglobulin subclasses IgG1,IgG2, IgG3, IgG4

Immunoglobulin subclasses IgG1,IgG2, IgG3, IgG4

Age related reference ranges ( all values in g/L):-

Cord Blood  IgG1=3.6-8.4, IgG2=1.2-4.0, IgG3 = 0.3-1.5, IgG4 = <0.5

6 months IgG1=1.5-3.0, IgG2= 0.3-0.5, IgG3 = 0.1-0.6, IgG4= <0.5

2 years  IgG1= 2.3-5.8, IgG2= 0.3-3.9, IgG3= 0.1-0.8, IgG4 = <0.5

5 years  IgG1= 2.3-6.4, IgG2= 0.7-4.5, IgG3= 0.1-1.1, IgG4 = <0.8

10 years IgG1= 3.6-7.3, IgG2= 1.4-4.5, IgG3= 0.3-1.1, IgG4 = <1.0

15 years IgG1= 3.8-7.7, IgG2= 1.3-4.6, IgG3= 0.2-1.2, IgG4 = <1.1

Adult     IgG1=3.2-10.2, IgG2= 1.2-6.6, IgG3= 0.2-1.9, IgG4 = <1.3

 

IgG1, IgG2, IgG3 and IgG4 ranges are sourced from Protein Reference Unit (PRU) Sheffield and last updated 14th January 2013 (http://www.immqas.org.uk/pru.asp?ID=316)

Infliximab drug monitoring

Infliximab drug monitoring

Please use drug levels as a guide. Infliximab Interpretation: Therapeutic drug levels: >2 µg/mL Intermediate drug levels: 1.0 – 2.0 µg/mL Subtherapeutic drug levels: < 1.0 µg/mL Test interpretation requires full clinical information: drug dosage/frequency, previous exposure to other biologics, time of sampling, duration of therapy and clinical assessment.

Infliximab drug monitoring

Infliximab drug monitoring

Please use drug levels as a guide. Infliximab Interpretation: Therapeutic drug levels: >2 µg/mL Intermediate drug levels: 1.0 – 2.0 µg/mL Subtherapeutic drug levels: < 1.0 µg/mL Test interpretation requires full clinical information: drug dosage/frequency, previous exposure to other biologics, time of sampling, duration of therapy and clinical assessment.

Inhibin A

Inhibin A

Female range - post menopausal 0 - 3.6 pg/mL.

Values in the premenopausal female vary with the stage of cycle 5 - 160 pg/mL.

Male range - 0 - 3.6 pg/mL.

Reference ranges established by manufacturer and validated in-house.

Inhibin A

Inhibin A

Female range - post menopausal 0 - 3.6 pg/mL.

Values in the premenopausal female vary with the stage of cycle 5 - 160 pg/mL.

Male range - 0 - 3.6 pg/mL.

Reference ranges established by manufacturer and validated in-house.

Inhibin B

Inhibin B

Inhibin B reference ranges

Adult male:25-325 ng/L
Adult female:<341 ng/L
Post-menopause:<5 ng/L

Values in premenopausal women vary with the stage of cycle, with maximal values beting seen five to ten days after the LH surge.

HRT will artificially stimulate inhibin B production in the menopause.

 

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