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Referred Work

 Functional C1 esterase inhibitor

Functional C1 esterase inhibitor

expressed as a percentage of a control serum with 75% -125% being classed as normal.

Acylcarnitines

Acylcarnitines

Provided by Reference Laboratory

Adalimumab drug monitoring

Adalimumab drug monitoring

Lower limit of the therapeutic range is yet to be established, however levels of greater than 5 µg/mL appear to be adequate.This information will be updated as we refine the therapeutic range. Test interpretation requires full clinical information: drug dosage/frequency, previous exposure to other biologics, time of sampling, duration of therapy and clinical assessment.

Adalimumab drug monitoring

Adalimumab drug monitoring

Lower limit of the therapeutic range is yet to be established, however levels of greater than 5 µg/mL appear to be adequate.This information will be updated as we refine the therapeutic range. Test interpretation requires full clinical information: drug dosage/frequency, previous exposure to other biologics, time of sampling, duration of therapy and clinical assessment.

Alkaline Phosphatase (ALP) Isoenzymes (APISO)

Alkaline Phosphatase (ALP) Isoenzymes (APISO)

Reported as a comment:

ALP1

Predominantly liver isoenzyme present.

ALP2

Predominantly bone isoenzyme present.

ALP3

Both liver and bone isoenzymes are present in approximately equal concentrations.

ALP4

Biliary isoenzyme also present.

ALP5

Intestinal isoenzyme also present: this may indicate intestinal disease but also may occur in the absence of pathology in some individuals of blood group O and B after eating.

ALP

Alkaline phosphatase isoenzyme analysis is not indicated when the total alkaline phosphatase is not markedly raised.

Alpha Subunits (ASU)

Alpha Subunits (ASU)

  • Adult males and pre-menopausal females: <1.0 IU/L
  • Post-menopausal or mid-cycle females: <3.0 IU/L

Pregnancy - there is a 0.1% cross reaction with hCG resulting in very high ASU results in pregnancy.

Results should be interpreted along with the serum LH, FSH and TSH results and renal function tests.

Anti C1q antibody

Anti C1q antibody

Supplied by reference laboratory

0 – 20 units/ml

Aquaporin 4 antibodies (AQP4)

Aquaporin 4 antibodies (AQP4)

Normal result is negative

Carbamazepine

Carbamazepine

Therapeutic range: 4-12 mg/L

Source : Pathology Harmony Recommendations

Nystagmus, ataxia and drowsiness occur at levels above 12 mg/L and more serious toxicity above 15 mg/L.

Cyclosporin

Cyclosporin

Bone Marrow Transplant 90 – 200 μg/L

Kidney Transplant 85 – 175 μg/L

 

 

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