Items starting with G

0-5 IU/mL Negative

Provided by reference laboratory.

12-64 IU/L (Males)
9-36 IU/L (Females)

Source : Abbott Diagnostics

Gamma-hydroxybutyrate (GHB) has been employed as an anaesthetic agent but is now more widely used and abused for its sedative properties. Toxic effects (euphoria, dizziness and unconsciousness) usually occur around 15 minutes post ingestion and last on average for about 3 hours. It has been found that blood concentrations above 260 mg/L were associated with deep sleep, 156 – 260 mg/L with moderate sleep, 52 – 156 mg/L with light sleep and levels less than 52 mg/L with wakefulness.

Negative

Provided by reference laboratory

Multiple Daily Dosing

Pre dose (trough) blood sample 15 mins before dose <2mg/L

Post dose (peak) blood sample 1 hour after dose 5 - 10mg/L

In endocarditis pre dose <1mg/L and post dose 3 - 5mg/L

N.B. Ranges and comments DO NOT apply to Renal patients

Once Daily Dosing

Post-dose only taken between 6 and 14 hours after dose. Times of dosing and sampling must MUST be given on request form.

Refer to Urban & Craig nomogram to interpet

Please refer to Antibiotic guidelines on the HEFT website for further information (http://pharmacy/?page_id=922)