a b c d e f g h i j k l m n o p q r s t u v w x y z #

Biochemistry

Referred Work (108)

Blood Sciences - Biochemistry referred work. These tests are available via the standard electronic and paper request cards. Site specific processing will be detailed in the test information. These tests are referred to other laboratories for analysis.

Solihull Biochemistry Laboratory (2)

Solihull Blood Sciences - Biochemistry - Test menu. These tests are available routinely on the Solihull Hospital site and/or may required site specific sample processing. All other biochemistry tests are available, but site specific processing may be required. This section details those tests

Heartlands Biochemistry Laboratory (27)

Heartlands Blood Sciences - Biochemistry - Test menu. These tests are available routinely on the Heartlands site and/or may required site specific sample processing. All other biochemistry tests are available, but site specific processing may be required. This section details those tests

Good Hope Biochemistry Laboratory (2)

Good Hope Blood Sciences - Biochemistry - Test menu. These tests are available routinely on the Good Hope site and/or may required site specific sample processing. All other biochemistry tests are available, but site specific processing may be required. This section details those tests

Triglycerides

0-1.7 mmol/L

Source : Abbott Diagnostics

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/triglycerides/tab/glance

Trimethylamine (Quantitative)

Provided by referral laboratory

Please note from 13 Feb 2017 new reference ranges and tests reported for TMA profile. TMA/TMA-n-oxide result has been replaced by % N-oxidation. Dimethylamine is no longer routinely analysed as part of the TMA profile - if it is required it should be requested separately.

PLEASE NOTE FROM JANUARY 2018 TOTAL TMA/CREATININE RATIO WILL NO LONGER BE REPORTED. The parameter is not directly required for diagnosis and is an assessment of the amount of dietary choline going through the pathway, which aids in the interpretation of results. The parameter will still be measured but not reported, rather a comment will be added if the value is low indicating insufficient stressing of the pathway which could lead to a false negative.

Referred Work Biochemistry

http://en.wikipedia.org/wiki/Trimethylaminuria

Troponin I - High Sensitive

The cut-off values used for the Abbott Alinity Troponin I assay are based on 99th percentiles and are as below:

Male <34 ng/L
Female <16 ng/L

Biochemistry

Unsaturated Iron Binding Capacity (UIBC)

UIBC: 12-43 µmol/L (Males), 13-56 µmol/L (Females)

(Source : Abbott Diagnostics)

TIBC: 45-72 µmol/L (TIBC = Iron + UIBC)

For diagnostic purposes, UIBC should always be assessed in conjunction with the patient’s medical history, clinical examinations and other findings.

Biochemistry

https://pinboard.in/u:duty_biochemist/t:UIBC/

Urea (Serum)

Neonates (<4weeks) 0.8-5.5 mmol/L

Infant (4wks-1yr) 1.0-5.5 mmol/L

1-16yrs 2.5-6.5 mmol/L

Adult 2.5-7.8 mmol/L

(Source : Pathology Harmony Recommendations)

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/urea/tab/test

Urea (Urine)

428-714 mmol/24h

Source : Abbott Diagnostics

Biochemistry

Urine Citrate

Provided by Reference Laboratory:

24 hour excretion:

Males : 0.6 ‑ 4.8 mmol/24 h

Females : 1.3 ‑ 6.0 mmol/24 h.

Random excretion (Citrate/creatinine ratio):

Males : 0.04 ‑ 0.33 mmol/mmol creatinine

Females :0.11 ‑ 0.55 mmol/mmol creatinine

Referred Work Biochemistry

Urine Cobalt

Normal values <2 nmol/mmol creatinine

Referred Work Biochemistry

https://pinboard.in/u:duty_biochemist/t:cobalt/

Urine Electrolytes

None Given. The results must be interpreted together with serum electrolytes and clinical details.

Biochemistry

https://pinboard.in/u:duty_biochemist/t:sodium/ https://pinboard.in/u:duty_biochemist/t:potassium/

Urine Iron

Provided by Reference Laboratory

Referred Work Biochemistry

https://pinboard.in/u:duty_biochemist/t:iron/

Urine Manganese

Provided by Reference Laboratory.

Urine: < 1µg / g creatinine (< 2 μmol/mol creatinine)

Referred Work Biochemistry

Urine Metanephrines

Table 1. 24hr Urine Metadrenaline Ranges

Analyte	Age	Collection	µmol/ 24 hr	Source
Normetadrenaline	Adult	24 hr	<4.9	Locally derived
	0-2 months	24 hr	<0.85	Tietz
	3-5 months	24 hr	<0.61
	6-8 months	24 hr	<0.6
	9-11 months	24 hr	<0.56
	1yr	24 hr	<0.65
	2-5 yr	24 hr	<0.6
	6-9 yr	24 hr	<0.96
	10-15 yr	24 hr	<1.59
Metadrenaline	Adult	24 hr	<2.0	Tietz
	0-2 months	24 hr	<0.19
	3-8 months	24 hr	<0.21
	9-11 months	24 hr	<0.51
	1 yr	24 hr	<0.26
	2-5 yr	24 hr	<0.5
	6-9 yr	24 hr	<0.7
	10-15 yr	24 hr	<1.23
3 MT	Adult	24 hrs	<2.75	Measurement of urinary metanephrines to screen for pheochromocytoma in an unselected hospital referral population. Shine Bet al. Clin Chem 2006 Nov;52(11):2060-4. Epub 2006 Sep 21
	0- 4 years	24 hrs	<0.62	Paediatric Reference Values for Urinary Catecholamine Metabolites Evaluated by High Performance Liquid Chromatography and Electrochemical Detection1
	5-15 years	24 hrs	<1.26

Table 2. Random Urine Metadrenaline Ranges

Analyte	Age	Collection	umol/mmol creatinine	Source
Normetadrenaline	Adult	Random	<0.35	Locally derived
	0-2 months	Random	<1.32	Chromsystems Dialog Magazine, 2009, http://chromsystems.com/en-gb/news/dialog
	3-5 months	Random	<0.91
	6-11 months	Random	<0.57
	1yr	Random	<0.35
	2-4 yr	Random	<0.24
	5-9 yr	Random	<0.16
	10-15 yr	Random	<0.11
Metadrenaline	Adult	Random	<0.11	Locally derived
	0-5 months	Random	<0.21	Chromsystems Dialog Magazine, 2009, http://chromsystems.com/en-gb/news/dialog
	6-11 months	Random	<0.13
	1 yr	Random	<0.12
	2-4 yr	Random	<0.11
	5-9 yr	Random	<0.10
	10-15 yr	Random	<0.07
3MT	Adult	Random	<0.15	Locally derived
	<1yr	Random	<1.5	Annales de Biologie Clinique. Volume 60, Numéro 1, 15-36, Janvier - Février 2002
	1 yr	Random	<0.75
	2-15 yr	Random	<0.36

Biochemistry

Urine Nickel

Normal range:

< 5 μmol/mol creatinine
< 5 μg/24 hr
< 85 nmol/24 hr

Referred Work Biochemistry

Urine NTX (N-telopeptide; bone marker/bone markers)

Reference ranges provided by referral laboratory (July 2014).

NB: Results are expressed as nmol bone collagen equivalent (BCE)/mmol creatinine.

Adult males: 15-40 nmol BCE/mmol

Adult females:

pre-menopause 20-39 yrs 12-36 nmol BCE/mmol

pre-menopause >39 yrs 14-38 nmol BCE/mmol

post-menopause 15-57 nmol BCE/mmol

Referred Work Biochemistry

Urine NTX (N-telopeptide; bone marker/bone markers)

Reference ranges provided by referral laboratory (July 2014).

NB: Results are expressed as nmol bone collagen equivalent (BCE)/mmol creatinine.

Adult males: 15-40 nmol BCE/mmol

Adult females:

pre-menopause 20-39 yrs 12-36 nmol BCE/mmol

pre-menopause >39 yrs 14-38 nmol BCE/mmol

post-menopause 15-57 nmol BCE/mmol

Referred Work Biochemistry

Urine Osmolality

None Given

Biochemistry

http://www.pinboard.in/u:duty_biochemist/t:osmolality/

Urine Oxalate

From 10/5/2018 refernce ranges will be:

100 - 460 umol/24 hour (adults, correct to 1.73m²for children)

Age related ref ranges for oxalate:creatinine ratio:

0-6 months <291µmol/mmol

7-23 months <220µmol/mmol

2-4 years <143µmol/mmol

5-11 years <76µmol/mmol

12 -17 years <44µmol/mmol

18+ female <45µmol/mmol

18+ male <33µmol/mmol

Referred Work Biochemistry

Urine Protein:Creatinine ratio (Random urine)

<15 mg/mmol Creatinine = Normal
15 – 49 mg/mmol Creatinine = Trace Proteinuria. Consider ACEI or ARB in diabetes.
50 – 99 mg/mmol Creatinine = Significant proteinuria. Repeat using early am sample. Consider ACEI or ARB in hypertension.
100 – 300 mg/mmol Creatinine = High proteinuria. If new finding, seek nephrology advice regardless of eGFR.
>300 mg/mmol Creatinine = “Nephrotic range” proteinuria. If new finding, seek nephrology advice regardless of eGFR.

Proteinuria is a risk factor for cardiovascular disease and for decline in GFR in CKD

UK CKD Guidelines suggest if PCR is >100 mg/mmol patient should be referred to Nephrologists irrespective of GFR.

Source of Reference Range: NICE guideline CG73 (2008) and UK eCKD guidelines 2009.)

Biochemistry

https://pinboard.in/u:duty_biochemist/t:ACR/ http://www.nice.org.uk/nicemedia/live/12069/42117/42117.pdf http://www.renal.org/information-resources#sthash.FvEFhUZh.dpbs

Urine PYD and DPD (bone marker/bone markers)

Reference ranges provided by referral laboratory (July 2014). All ranges expressed as nmol/mmol creatinine.

	Males		Females
	PYD/Cre	DPD/Cre	PYD/Cre	DPD/Cre
4-5 yrs	58.7-85.0	17.4-24.3	63.7-85.1	17.2-25.1
5-6 yrs	54.7-83.0	15.9-22.5	55.7-82.9	14.8-22.1
6-7 yrs	53.0-76.7	14.8-22.3	57.6-77.5	13.8-21.2
7-8 yrs	51.6-72.2	14.6-22.1	55.3-75.1	15.2-21.0
8-9 yrs	46.1-63.4	12.0-16.1	49.9-66.9	12.6-18.4
9-10yrs	49.5-67.3	12.3-16.3	58.5-79.4	15.7-22.4
10-11 yrs	45.7-67.4	12.6-18.8	47.3-71.5	13.2-18.9
11-12 yrs	45.5-66.3	12.4-18.6	50.6-88.8	14.9-25.3
12-13 yrs	43.6-56.6	11.7-17.4	46.3-73.6	13.1-22.1
13-14 yrs	42.6-84.5	11.2-23.9	44.1-65.3	11.9-18.2
14-15 yrs	40.7-89.3	10.9-25.6	35.3-52.5	8.7-17.6
15-16 yrs	35.4-84.3	9.8-22.2	26.5-48.8	5.1-14.9
16-17 yrs	28.8-68.3	7.1-18.7	19.6-37.1	3.0-9.4
Adult	5.0-21.8	0.4-6.4	pre-menopause 20-39yrs: 7.8-20.4	1.8-6.4
			pre-menopause >40 yrs: 8.1-21.2	2.1-6.7
			post-menopause: 7.1-31.8	1.5-8.6

Referred Work Biochemistry

Urine PYD and DPD (bone marker/bone markers)

Reference ranges provided by referral laboratory (July 2014). All ranges expressed as nmol/mmol creatinine.

	Males		Females
	PYD/Cre	DPD/Cre	PYD/Cre	DPD/Cre
4-5 yrs	58.7-85.0	17.4-24.3	63.7-85.1	17.2-25.1
5-6 yrs	54.7-83.0	15.9-22.5	55.7-82.9	14.8-22.1
6-7 yrs	53.0-76.7	14.8-22.3	57.6-77.5	13.8-21.2
7-8 yrs	51.6-72.2	14.6-22.1	55.3-75.1	15.2-21.0
8-9 yrs	46.1-63.4	12.0-16.1	49.9-66.9	12.6-18.4
9-10yrs	49.5-67.3	12.3-16.3	58.5-79.4	15.7-22.4
10-11 yrs	45.7-67.4	12.6-18.8	47.3-71.5	13.2-18.9
11-12 yrs	45.5-66.3	12.4-18.6	50.6-88.8	14.9-25.3
12-13 yrs	43.6-56.6	11.7-17.4	46.3-73.6	13.1-22.1
13-14 yrs	42.6-84.5	11.2-23.9	44.1-65.3	11.9-18.2
14-15 yrs	40.7-89.3	10.9-25.6	35.3-52.5	8.7-17.6
15-16 yrs	35.4-84.3	9.8-22.2	26.5-48.8	5.1-14.9
16-17 yrs	28.8-68.3	7.1-18.7	19.6-37.1	3.0-9.4
Adult	5.0-21.8	0.4-6.4	pre-menopause 20-39yrs: 7.8-20.4	1.8-6.4
			pre-menopause >40 yrs: 8.1-21.2	2.1-6.7
			post-menopause: 7.1-31.8	1.5-8.6

Referred Work Biochemistry

<< < 8 9 10 11 12 [13] 14 > >>