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Heartlands Biochemistry Laboratory

Sweat Sodium

Sweat sodium is used as a check of the chloride result. Interpretation is as follows:

Cystic fibrosis unlikely < 50 mmol/L

Supports the diagnosis of CF > 90 mmol/L

The Sodium and Chloride concentrations should be within 20 mmol/L of each other.

Sweat sodium is used as a check of the chloride result. Interpretation is as follows:

Cystic fibrosis unlikely < 50 mmol/L

Supports the diagnosis of CF > 90 mmol/L

The Sodium and Chloride concentrations should be within 20 mmol/L of each other.

This is a screening test. Drugs detected in specimens will be stated on the report.

THIS ASSAY IS CURRENTLY NOT AVAILABLE

TPMT phenotype/activity reference ranges:

<6 nmol/ghb/hr = Deficient

6-34 nmol/gHb/hr = Low

35-79 nmol/gHb/hr = Normal

>79 nmol/gHb/hr = High

TPMT genotype classifications:

WT = wild-type, normal result

H3 = TPMT 1*/3* - heterozygous for TPMT, this would indicate a reduced activity. Advise reduce dose of azothioprine.

H2 = TPMT 1*/2* - heterozygous for TPMT, this would indicate a reduced activity. Advise reduce dose of azothioprine

H03 = TPMT 3*/3* - homozygous for TPMT, this would indicated deficient TPMT activity. Advise stop treatment with azothioprine.

H02 = TPMT 2*/2* - homozygous for TPMT, this would indicated deficient TPMT activity. Advise stop treatment with azothioprine.

A toxicology screen is qualitative result and as such, an interpretative report will be issued.

<15 nmol/L - Severe vitamin D deficiency

15-25 nmol/L - Vitamin D deficiency,

25-50 nmol/L - Vitamin D insufficiency,

50 nmol/L or greater - Adequate vitamin D status.

Signs of vitamin D toxicity maybe seen at levels greater than 250 nmol/L

Source of ranges =

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