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Items starting with T

Thyroglobulin

No reference ranges applicable. Results must be interpreted with thyroglobulin antibodies (TgAb).

Successfully treated post-thyroidectomy patients should have an undetectable serum thyroglobulin. Elevations in thyroglobulin post-thyroidectomy for DTC can indicate recurrence of disease or metastasis. Thyroglobulin analysis is most sensitive when TSH is not suppressed ie, any small thyroid remnants of disease present should produce measurable thyroglobulin.

Interpretation of results also depends on factors such as whether the patient is on T4/T3 replacement.

Higher levels may be seen in the newborns and in the third trimester of pregnancy.

Benign elevations of thyroglobulin see with:

Grave's disease
Hashimoto's disease
Adenomas

Biochemistry

NICE guidance NG230

Thyroid Antibodies (Thyroid Peroxidase Antibody)

< 5.61U/mL - Negative

> 5.62 <30 IU/mL - Equivocal

>30 IU/mL - Positive

Immunology

http://www.labtestsonline.org.uk/understanding/analytes/thyroid-antibodies/tab/faq

Thyrotrophin (TSH)

TSH - 0.4-4.9 mIU/L

(source: Abbott Diagnostics)

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/tsh/tab/glance

Tissue Transglutaminase Antibodies (TTG)

Negative = <7 U/mL

Weak positive = 7-10 U/mL

Positive = >10 U/mL

Normal result = Negative

Immunology

Tissues, Biopsies and Lymph Nodes - Microscopy, Culture & Susceptibility

Microbiology

https://www.heftpathology.com/departments-list/microbiology/140-general-details.html

Tobramycin Antibiotic Assay

Multiple Daily Dosing

Pre dose (trough) blood sample 15 mins before dose < 2mg/L

Post dose (peak) blood sample 1 hour after dose 5 - 10mg/L

N.B. Ranges and comments DO NOT apply to Renal patients

Once Daily Dosing

Pre dose (trough) < 1 mg/L

Please refer to Antibiotic guidelines on the HEFT website for further information (http://pharmacy/?page_id=922)

For diagnostic purposes, the test findings should always be assessed in conjunction with the patient’s medical history, clinical examinations, and other findings

Microbiology Biochemistry

http://www.heftpathology.com/Microbiology/micro-antibiotic-assay-protocol.html

Total Protein (CSF)

0.15 - 0.4 g/L (Source: Abbott laboratories)

Biochemistry

Centrifuge all samples at 3200 rpm for 10 minutes prior to analysis.

Total Protein (serum)

60-80 g/L

(Source : Pathology Harmony Recommendations)

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/tp/tab/glance

Total Protein (Urine)

0.01-0.14g/L

Source : Abbott Diagnostics

Biochemistry

http://www.labtestsonline.org.uk/understanding/analytes/urine-protein/tab/faq

Toxicology Screen (Urine & Serum)

A toxicology screen is qualitative result and as such, an interpretative report will be issued.

Toxicology Heartlands Biochemistry Laboratory Biochemistry

Toxocara

Microbiology

Toxoplasma IgG screen

Microbiology

Toxoplasma IgM screen

Microbiology

Toxoplasma PCR

Microbiology

Tramadol

High dose therapeutic use of tramadol associated with concentrations of up to 0.8 mg/L. Toxicity associated with concentrations > 1 mg/L. (Schulz et al. Critical Care 2012, 16:R136).

Toxicology

Transferrin

Transferrin Reference ranges:

1 to 14 years	Male	1.86 - 3.88
1 to 14 years	Female	1.80 - 3.91
> 14 to 60 years	Male	1.74 - 3.64
> 14 to 60 years	Female	1.80 - 3.82
> 60 to 80 years	Male	1.63 - 3.44
> 60 to 80 years	Female	1.73 - 3.60

Biochemistry

Transferrin Electrophoresis for diagnosis of CDGs (Also known as: Transferrin isoelectric focusing, TfIEF)

Provided by reference laboratory

Biochemistry

Trazodone

Therapeutic range: 0.70 -1.0 mg/L. Toxicity associated with concentrations > 1.2 mg/L. (Schulz et al. Critical Care 2012, 16:R136).

However, tolerance for the drug varies greatly between indiciduals. Please contact the laboratory for interpretation.

Toxicology

Trichinella

Microbiology

Trichomonas PCR

Microbiology

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